Start by describing the work the software must support. List the tasks, people involved, information created, and problems with the current process. This prevents attractive features from distracting you from the real need.
Next, compare ease of use, compatibility, security, support, and total cost. A tool that fits existing habits may be more useful than one with a longer feature list.
Before making a final decision, test the software with a small, realistic task. Ask the people who will use it to record what feels confusing, slow, or unnecessary.